One well-known element of aging is a molecule called NAD Nicotinamide Adenine Dinucleotide (find out more here). The amount of this coenzyme present in the body has an impact on the rate at which the body ages. Levels of NAD+ will be higher in younger tissues, which explains why younger people tend to have more energy, better physical activity performance, better cognitive function, and better cell regeneration than older people. Despite the fact that NAD levels naturally fall with age, several approaches such as oral supplementation can help to boost them.
What Are Normal Levels Of NAD+ For Each Age Group?
Typical NAD levels vary considerably by age and unit of measurement. NAD levels within cells can range between 10 and 1000 μM. Additionally, total NAD values were observed to range between 0.3 and 0.4 μmol/g. These levels gradually decrease as one ages.
Levels Of NAD+ Drops 50% at 40s.
By the time a person reaches middle age, NAD+ levels have declined to half of their young levels, leading to the loss of sirtuin and PARP activity in the brain.
Several common elements of aging, such as oxidative stress, mitochondrial dysfunction, and the inflammatory response, can all result in reductions in NAD concentrations. As people get older, their levels of NAD+ begin to decline. This is also the case for certain conditions such as metabolic disorders, cancer, and neurological diseases.
Given that NAD is responsible for assisting in the restoration and repair of the mind and body, low levels of NAD+ can result in a variety of problems. One of these problems is a reduction in autophagy. Autophagy is a cellular process that is responsible for the protection of cell structures. Another issue that arises when NAD levels fall is a decrease in the regulation of gene expression, as well as a drop in mitochondrial biogenesis (the production of mitochondria).
How To Boost Levels Of NAD+?
The levels of NAD+ can be naturally raised by engaging in physical activity, reducing your exposure to the sun, optimizing your nutrition and boosting it through precursor of NAD NMN supplementation via oral or IV infusion forms.
By maintaining high levels of NAD+ levels, you can slow down the aging process by repairing damaged cells and DNA. This may enhance energy. NAD also aids in metabolic activity, which aids in tiredness reduction and weight loss. Because metabolism influences nearly every human function, NAD promotes a healthy metabolism.