What is Spermidine?
Spermidine is a polyamine that naturally occurs and is also referred to as trihydrochloride spermidine. It is extensively dispersed in many different human body cells, particularly in ribosomes, in addition to semen.
Spermidine is crucial for the survival and operation of cells. Polyamines have the ability to attach to a wide range of molecules, boosting cell development, stabilizing DNA, and facilitating both apoptosis and proliferation of cells.
Moreover, foods including grapefruit, soy products, beans, maize, and whole grains contain spermidine. Yet, food has relatively little spermidine in it. It may be worthwhile to think about taking supplements containing spermidine, such as the well regarded Rescence Pure Spermidine 15000, for people who desire to obtain longevity advantages by supplementing with spermidine.
Benefits of Spermidine
Spermidine has various benefits, including improving hypertension, anti-aging, preventing dementia, anti-inflammatory, anti-cancer, improving liver health, improving neurological health, and enhancing immunity. It is also one of the few substances that protect sperm.
The following detailed spermidine benefits can be referenced:
- Promoting autophagy – Autophagy is a cellular cleaning mechanism that helps to remove excess and damaged components within cells.
- Spermidine can activate the autophagy process, helping to maintain cellular health.
- Delaying aging – Spermidine or polyamine-rich diets can prevent cellular aging, prolonging lifetime in humans and animals.
- Anti-inflammatory actions – Spermidine reduces chronic inflammatory responses and the risk of chronic illnesses.
- Spermidine improves blood vessel flexibility, lowers blood pressure, and lowers the risk of atherosclerosis.
- Anti-cancer properties – Spermidine inhibits cancer cell proliferation and spread, according to several research.
- Neurological health – Spermidine protects nerve cells, lowering the risk of neurodegenerative disorders like Parkinson’s and Alzheimer’s and enhancing stress resistance.
- Preventing liver fibrosis and hepatocellular cancer using spermidine.
SUGGESTED USE OF SPERMIDINE SUPPLEMENT
Dissolve your desired dosage based on its weight in a fat food source or ingest or along with a meal, 2/3 scoop measures approximately ~500 mg (this can vary based on every batch and the product’s density).
WARNINGS OF SPERMIDINE SUPPLEMENT
- Do not use if safety seal is broken or damaged.
- Individuals with allergies to any ingredients should not take this product.
- Avoid direct sunlight. Store tightly in a cool, dry place below 25°C / 77°F within 24 months. Store in the fridge or freezer after opening.
- Always consult your health professional before using this product, particularly if you are pregnant, breastfeeding, children under the age of 18, are aware of a medical condition or are taking any medication.
Pure SPD Spermidine 15000 – Cellular Revival and Reverse Hallmarks of Aging
Rescence Pure SPD Spermidine 15000 contains effective spermidine, naturally occurring polyamines vital to human health. Each gram of Pure SPD 15000 renders 1% / 10 mg of spermidine, a very high dosage of spermidine. Spermidine has been proved to combat 6 out of 9 hallmarks of aging through primarily its superb autophagy function. It is anti-inflammatory, cardioprotective, neuroprotective considerably supporting healthspan.
Find out what SPD spermidine is in this article.
The statements above have not been evaluated by any food and drug administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
FAQ of Pure Spermidine 15000
Why do we need to boost spermidine level?
Spermidine (SPD) is a powerful polyamine renowned for promoting autophagy, the cellular regeneration and recycling mechanism of the body that decreases with age. As you age, your body produces less spermidine, making it tougher for cells to activate autophagy.
Restoring spermidine to its youth levels has had astounding effects such as the below (research summary)as shown in many clinical researches:
- Longevity
- Boost stress tolerance
- Improves cardiovascular function
- Enhances fertility
- A Neuroprotective agent
- Cancer prevention
- Reduces age related complications
- Enhances function of hair follicles
What is the suggested dosage of SPD spermidine? How much does Harvard Professor Dr. David Sinclair take?
The recommended daily amount of spermidine supplement is no more than 6 mg.
Spermidine is a powerful compound that stimulates autophagy and also have stabilizing effects on the epigenome. The highest dose tested in humans was 6mg once daily, and that was in a single study. Up until now, 1-6mg of spermidine per day has been the standard for the majority of investigations.
Another current human study uses proven ways to investigate if older people may safely take a daily spermidine supplement after having a SARS-CoV-2 booster injection.
Professor of anti-aging genetics at Harvard, Dr. David Sinclair, stated in a recent interview that he takes 1 mg of spermidine on a regular basis.
Check out this article for dosing advice.
What are the benefits of spermidine supplement?
Spermidine for hair growth. The study indicated that spermidine supplementation of 0.5 mg can support hair growth and strength.
Spermidine for cardiovascular health. According to a research, use of spermidine supplement of 4 mg/daily for 8 weeks reduces the risk of hypertension, heart failure, and other cardiovascular issues.
Spermidine to support cognitive function. A study indicates that the dosage of 1.2 mg of spermidine for 3 months reduced age-related cognitive decline and risk of Alzheimer’s.
Spermidine to slow down aging. One study found a connection between higher spermidine consumption from dietary sources such as supplements and improved human survival rates.
How to take SPD spermidine? What is the suggested usage of SPD spermidine?
Spermidine is most effective when taken in the morning at the same time every day and recommended to ingest along with food to enhance their absorption.
As a David Sinclair, the longevity genetic expert and Harvard professor, takes spermidine in the morning.
How to store Rescence Pure Spermidine at home?
Rescence Pure SPD Spermidine should be stored tightly inside an opaque container, avoiding direct sunlight, in a cool and dry place below 25°C / 77°F for up to 24 months.
References of Spermidine Supplement
Wirth, M., Benson, G., Schwarz, C., Köbe, T., Grittner, U., Schmitz, D., Sigrist, S. J., Bohlken, J., Stekovic, S., Madeo, F., & Flöel, A. (2018). The effect of spermidine on memory performance in older adults at risk for dementia: A randomized controlled trial. Cortex, 109, 181–188. https://www.sciencedirect.com/science/article/abs/pii/S0010945218303137?viaihub
Kiechl, S., Pechlaner, R., Willeit, P., Notdurfter, M., Paulweber, B., Willeit, K., Werner, P., Ruckenstuhl, C., Iglseder, B., Weger, S., Mairhofer, B., Gartner, M., Kedenko, L., Chmelikova, M., Stekovic, S., Stuppner, H., Oberhollenzer, F., Kroemer, G., Mayr, M., & Eisenberg, T. (2018). Higher spermidine intake is linked to lower mortality: a prospective population-based study. The American Journal of Clinical Nutrition, 108(2), 371–380. https://doi.org/10.1093/ajcn/nqy102
University of Oxford. (2022). Improving Vaccination in Older Adults by Inducing Autophagy With Spermidine. https://ichgcp.net/clinical-trials-registry/NCT05421546
Dirk Von Lewinski, A., Sedej, A., Tobias Eisenberg, A., & Abdellatif, M. (n.d.). Protovol (Version 3.1 -updated 23MAY2020) Spermidine Anti-Hypertension Study (SMARTEST) Effect of spermidine on arterial blood pressure in hypertensive patients. Retrieved March 28, 2023, from https://clinicaltrials.gov/ProvidedDocs/88/NCT04405388/Prot_SAP_000.pdf
Alice. (2021, March 10). Metabolite of the month – Spermidine – biocrates life sciences ag. https://biocrates.com/metabolite-of-the-month-spermidine/#:~:text=In%20vitro%20studies%20on%20human
