Benefits of Resveratrol
It has garnered considerable interest due to its purported anti-aging and disease-fighting properties. For a long time, researchers believed that some components of red wine may have health advantages. Experts began focusing on resveratrol, an antioxidant molecule found in red wine, in the 1990s. Since then, other animals and laboratory investigations have demonstrated that resveratrol possesses antiviral, anti-inflammatory, and anticancer properties.
Resveratrol has been found in preclinical research to exhibit a variety of biological actions that may be used to prevent and/or cure cancer, cardiovascular disease, and neurological illnesses.
Resveratrol and Heart Health
- Resveratrol has been shown to reduce adhesion molecule expression in cultivated endothelial cells causing heart problems.
- It is believed to assist in reducing inflammation, lowering LDL or “bad” cholesterol, and making it more difficult for blood clots to develop, which can result in a heart attack.
- The proliferation of vascular smooth muscle cells (VSMCs)is linked to hypertension, atherosclerosis, and restenosis. Resveratrol inhibits VSMC growth in vitro and in vivo (inside the cell).
Resveratrol and Neurogenerative Disease Prevention
- A single oral dosage of 500 mg resveratrol increased cerebral blood flow in the prefrontal cortex of healthy young adults (ages 18-29).
- Age-related mood changes and memory deficiencies are caused by a decline in the hippocampus’s function in the aged subjects. Resveratrol has been demonstrated to promote neurogenesis and the development of blood vessels in the hippocampus of healthy elderly rats. Significant increases in spatial learning, memory formation, and mood function were connected with these structural modifications.
- It may protect nerve cells from damage and fight the plaque buildup that can lead to Alzheimer’s disease.
Resveratrol and Diabetes
- Resveratrol has been demonstrated to enhance insulin sensitivity, glucose tolerance, and lipid profiles in obese and/or metabolically dysfunctional animals in animal experiments.
- Short-term resveratrol supplementation has been linked to improved glucose and lipid metabolism in people with type 2 diabetes. The impact of oral resveratrol supplementation (1,000 mg/day for 45 days) on glucose metabolism was studied in 70 people with type 2 diabetes. The study found that resveratrol reduced fasting glucose and insulin levels and increased glycemic control (HbA1c) and insulin sensitivity (Isa) in both placebo and intervention groups (HOMA-IR). Also, HDL cholesterol improved while LDL-cholesterol and systolic blood pressure decreased.
- According to researchers, resveratrol stimulates the SIRT1 gene. This gene is thought to protect the body from the consequences of obesity and aging-related disorders.
Anticancer Effects of Resveratrol
- Apart from its anti-inflammatory, antioxidant, and cardioprotective (risk of heart disease reduction) qualities, resveratrol has been demonstrated to possess anticancer capabilities. Resveratrol has been found in laboratory and animal studies to exert anticancer activity via activating or deactivating molecular pathways.
- Resveratrol has been shown to decrease the growth of a number of human cancer cell lines, including those derived from breast, prostate, stomach, colon, pancreatic, and thyroid malignancies.
Resveratrol Effect on Fertility
- Resveratrol may provide therapeutic effects in women with impaired ovarian function, polycystic ovary syndrome (PCOS), endometriosis, or uterine fibroids, according to growing data.
- Additionally, resveratrol has been shown to enhance testicular function and sperm quality.
Skincare Benefits of Resveratrol
- One 2014 study found that topically applying resveratrol significantly improved fine lines, wrinkles, and elasticity in 12 weeks.
- Resveratrol has been shown to help protect against UV damage and may even help prevent sun-induced pigmentation
