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Free Radical Damage And Role Of Antioxidants

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What Are Free Radicals?

Free radicals are naturally occurring byproducts of the body’s continuous biochemical events, such as normal metabolic processes and immune system responses. Due to the presence of unpaired electrons, free radicals are extremely reactive with other biological structures. The food we eat, the pharmaceuticals and medicines we take, the air we breathe, and the water we drink all include free radical-generating compounds. Fried foods, alcohol, cigarette smoke, pesticides, and air pollution are only a few of these chemicals. By stealing electrons from components of cells such as proteins, DNA, and cell membranes, free radicals can cause damage. This process is termed oxidation. (This is why the free radical injury is often referred to as “oxidative injury.”).

When free radicals oxidize critical cell components, those components lose their capacity to function normally, and the accumulation of such damage may result in the cell’s death. Certain cells can repair themselves, whereas others cannot. According to scientists, chemicals known as free radicals may have a role in the aging process. They may also contribute to the development of illnesses such as cancer, diabetes, and heart disease. Numerous studies demonstrate that increased free radical generation results in or accelerates nerve cell damage and illness.

Role of Antioxidants versus Free Radicals

The term “antioxidant” does not refer to a specific chemical, but rather to the effect that a variety of compounds can have.

Antioxidants also referred to as “free radical scavengers,” are chemicals that either prevent the creation of free radicals or react with them and neutralize them. Antioxidants frequently function by giving an electron to the free radical, preventing it from oxidizing other cell components. Once the free radical’s electrons are coupled, it is stabilized and become non-toxic to cells. Antioxidant therapy targeted at boosting antioxidant availability in cells may be useful in preventing or reducing the progression of neurological illnesses. There are many antioxidants available naturally as well as in supplementation form but the most useful for longevity purposes is resveratrol.

Resveratrol possesses antioxidant and anti-inflammatory qualities that aid in the prevention of illnesses such as cancer, diabetes, and Alzheimer’s disease. Resveratrol’s anti-inflammatory properties make it an effective treatment for arthritis and skin irritation.  Researchers predict that resveratrol, based on animal and cellular studies, may be effective in combating several age-related illnesses and works as the best antioxidant.

  • Longevity. Increasing the longevity of animals by simulating the impacts of calorie restriction.
  • Reduction of inflammation. Multiple levels of oxidative stress and inflammation are reduced (enzymes, immune cells, gene expression).
  • Gene regulation. Turning off the genes that cause aging by activating SIRT1.
  • Bone Health. Resveratrol may work with vitamin D and vitamin K2 to preserve and strengthen bones.
  • Better Hearing. By neutralizing free radicals and improving blood flow in the ears of mice exposed to harmful noise, resveratrol protected against hearing loss.